The 50 Best Villains in Movie History

1. John Doe

Played By: Kevin Spacey
Movie: Se7en (1995)

John Doe's master plan is a work of strategic, perverse genius. Inspired by Christianity's seven deadly sins (lust, gluttony, greed, sloth, wrath, envy, and pride), the anonymous, mostly unseen (until Kevin Spacey shows up in Se7en's final act) serial killer handpicks each of his victims based on which of the aforementioned sins they're guilty of; thus, an obese man eats himself to death ("Gluttony"), and a criminal gets strapped to a bed, unfed and immobile, for one year, becoming "Sloth."

Doe's elaborate scheme reaches its apex of during Se7en's final sequence, a knockout battle of wills between the killer and Detective David Mills (Brad Pitt) that involves both "Envy" and "Wrath." Without spoiling it for those who've yet to see director David Fincher's dynamite thriller, let's just say that Mills gets played like a puppet. And all over a cardboard box. —MB

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