"What's Up With That" Returns f/ DJ Khaled, Charles Barkley, and Lindsey Buckingham

For the second episode of Saturday Night Live’s At Home series, Kenan Thompson took on the role of Diondre Cole, host of the show’s recurring sketch “What’s Up With That.”

In this edition, Thompson was joined by guests DJ Khaled, Charles Barkley, and Lindsey Buckingham (Bill Hader), as well as Thompson’s SNL crew Ego Nwodim, Melissa Villaseñor, Jason Sudeikis, Fred Armisen, Cecily Strong, and Mikey Day.

Cole kicks off his show with its theme song, also titled “What’s Up With That,” before introducing his guests. Barkley’s able to squeeze in a few sentences about his involvement in the Michael Jordan documentary The Last Dance, but per usual, Cole repeatedly reprises the theme song. Khaled barely says anything except his catchphrase, “another one” at the end of the show. And of course, Buckingham never gets a chance to talk.

For this weekend’s episode, Brad Pitt delivered the opening monologue as Dr. Anthony Fauci, where he cleared up some misconceptions about COVID-19. Pete Davidson also shared a new music video, “Stuck in the House,” which featured his mom’s home, Adam Sandler, and Rob Schneider. For the first At Home episode on April 11, Tom Hanks gave the cold open.