10. Freakazoid! (1995-1997, Kids' WB!)
In 1995, Bruce Timm and Paul Dini, two of the men responsible for Batman: The Animated Series, capitalized on the success of their superhero shows, along with the off-the-wall humor of Animaniacs, to bring Freakazoid to life. The show was about Dexter Douglas, a high school student who became infected with a computer bug that turned him into a blue-skinned being of pure insanity with super strength and speed. Along the way, Freakazoid put a beating on various supervillains and criminals with all of the subtlety of an anvil to the head.
Freakazoid was a fourth-wall breaking and surreal satire with an eye for mayhem and the bizarre. But despite the novel concept and memorable characters, the show only lasted a couple dozen episodes before being shown the door.