Released: 2005
Developer/Publisher: Capcom Production Studio 4 for Capcom
Platform(s): PS2, GC, Wii, PC

Rare is the game that takes an established, much-loved series and rips out its guts and reanimates it into an unbeatable classic. The movement is fluid, the atmosphere and intensity is ratcheted up, and the storyline is more cinematic than most multiplex offerings. Add hundreds of crazed, blank-eyed townies who will stop at nothing to lay their grimy hands on you, and you have the best RE ever. And that's saying something.

RE4 was originally to feature regular zombies as bad guys, but to avoid repeating formula, developers decided to make alien-possessed humans (called "Los Ganados") the enemies.