TV Show: Will & Grace

There's no question Debra Messing is a very pretty comedic actress. It's also pretty clear that her character Grace was the train wreck you spent your dating life trying to avoid. Grace was neurotic, she would eat her sadness, she was messy —sort of the Cathy comic-strip come to life, but with the possibly-redeeming power of beauty. 

Nowadays, Messing is taking a break from comedy by focusing on more dramatic fare. She's currently on NBC's musical drama, Smash.