50 Cent has constantly been trolling Floyd Mayweather Jr. on Instagram over the past few months but he may have just dropped his funniest video yet. Floyd made a comment that artists like 50, Nelly, and T.I. will "come and go" that hit the Internet this morning.

"What's so crazy is this: You know, when people are not relevant, and they're not moving units like they were once moving ... you've got to realize, I've been relevant for 18 years," Mayweather said in an interview with MLive.com50 must have woke up to the chatter, and hopped on Instagram immediately to address Floyd's comments—and with a ton of shade.

"I'm like what he say fuck me for, Nelly fucked your first baby momma Melissa, then took your fucking fiancé, say fuck that n***a," 50 said in the video.

Between the lack of fucks given, and his facial expressions, 50 really might be the King of Instagram right now.

50 wasn't done with one video though, as he returned to challenge Floyd to a special version of the Ice Bucket Challenge, where Floyd has to read one page of a Harry Potter book and 50 will donate $750,000 to charity.

UPDATE: 50 is back at it with another video. The caption reads, "Just in people, Jimmy Kimmel will let Floyd read live on his show if he accepts."