Song She Inspired:Derek and the Dominos - "Layla" (1970)
Highest Position on the Billboard Hot 100: 10

It's the greatest tale in rock 'n roll history of coveting thy neighbor's wife's ass. Eric Clapton was obsessed with Pattie Boyd, who happened to be the wife of his good friend George Harrison. There's actually another level to it. Since he couldn't have Pattie, ol' Slowhand moved in with her sister Paula. When Paula heard "Layla," she realized that Clapton was only with her because he couldn't have his sister, and that was the end of that relationship. Later, Harrison and Boyd's marriage did fall apart, and Clapton was there to pick up the pieces, marrying Pattie in 1979.