The BioShock series has so far hit on two incredibly unique locations: the underwater metropolis of Rapture, and the floating city of Columbia. They're separated by decades, miles and disparate founding philosophies. Really, the two cities couldn't possibly be more different.

But when it comes down to it, they have at least one thing in common: violent hordes of things that want to kill you.

From the splicers introduced in BioShock to the Big Sister that appeared only in BioShock 2, Rapture was truly a dangerous place. But how does it compare to Columbia, the quantum physics-powered sky-city feature in BioShock Infinite? Can a Handyman really compare to a Big Daddy? Who would win in a fight between a Vox Populi anarchist and a junkie splicer?

Those are the kinds of questions that might keep a hardcore BioShock fan up at night, and that's what prompted us to create this ultimate guide to the enemies of the BioShock universe. We tried to list them all, but if we left any off be sure to let us know in the comments or on Twitter!