Bill Murray In Zombieland (2009)
In Zombieland, Murray's role is part of an unexpected twist at the end of the film. When zombie apocalypse survivors Columbus (Jesse Eisenberg), Tallahassee (Woody Harrelson), Wichita (Emma Stone), and Little Rock (Abigail Breslin) break into a random house in Los Angeles, they're surprised to discover that it's actually Bill Murray's place—except for Little Rock, because she has no clue who he is.
Assuming he's dead, they take refuge in the mansion, only to discover later that Murray is alive, and he's just been putting on make-up to look like a zombie so he can survive amongst them. Tallahassee and Wichita discover this first, and instead of telling the remaining two in the group, they decide to play a trick on them that includes Murray sneaking up on them and acting like he's a zombie. This is pretty stupid, though, because zombies actually exist in this world, and Murray ends up with a gaping bullet hole in his chest courtesy of Columbus. In true Murray fashion, however, he's not all that mad, and he dies pretty peacefully.
Verdict: Have you seen Ghostbusters? This guy would totally rock a zombie apocalypse and live to tell the tale.