What They've Got In Common: Little sisters trying to keep their family together while everyone around them goes apeshit and acts like zombies for a crazy drug that (they think) gives them enhanced abilities? It's like Ken Levine wrote the script!
Fun Fact: Ayn Rand, whose Objectivist philosophies permeate the undersea Art Deco world of Rapture in BioShock, was also an esteemed meth chemist! In fact, Bryan Cranston prepared for his role in Breaking Bad by reading The Fountainhead. Also please don't sue us, any of the people or properties mentioned in the previous sentences. We're only kidding.