Album: Quicksand EP (2009)
Video Game: Bayonetta (2010)

Granted, La Roux's "Bulletproof" was a bigger commercial hit but "In for the Kill" catered way more to the sensibilities of the hipster crowd who got down with her before the hype. Not only did the commercial for Bayonetta use "In for the Kill" but it used a remixed version instead, leading to higher gains of hipster nerd credibility. Too bad Bayonetta's main fanbase were blue collar pervs and otaku weirdos.

Watch the Bayonetta commercial:

Listen to "In For the Kill Skream's Let's Get Ravey remix" on Spotify: