6. TORI SPELLING

When: April 5, 2009
Comment:  "I want to thank [Tori] for being able to take a joke. I'm going to try my hardest not to tell her she looks like a man anymore. It's not nice. Even if it's true, it's not nice."

Upon accepting her award for "Best Celebrity Autobiography" at the Bravo A-List Awards, Tori thanked Handler in her speech saying, "I want to thank you for finding ways to say I'm ugly and stupid, week after week." Later during the show, Handler responded with the comment above.