Age: 34

Over five hit-or-miss seasons, HBO’s hit series Entourage has turned Jeremy Piven into a star and helped Jerry Ferrara sleep with Jamie Lynn Sigler. Not bad for a program that’s been rehashing the same plot for almost seven years. Ho-hum leading man Adrian Grenier is the least interesting thing about Entourage, which is pretty sad, because, you know, he’s the main character. The forthcoming sixth season will be the show’s last hurrah, meaning its cast will have to evaluate their career options. Here’s a tip for Grenier: You’ll never be Vincent Chase in real life, so give it up.