Disease: Pandoran Bullymong Fleeze
Vault hunters have been heading to Pandora for years searching for riches and treasure. What most of them came back with was a crippling case of the Fleeze.
Originally a bacteria only found in the native Bullymong population, the parasite made the leap to Pandora's human population. The bacterium is an orally transmitted ailment that causes sufferers to develop sharp crystalline growths on the gums and lips.
It's basically an iced out version of herpes.