7. FRINGE (FOX, 2008-PRESENT)
Mystery: What is The Pattern?
Initially, the criminally slept-on sci-fi gem Fringe focuses on the mystery surrounding “The Pattern,” a strange series of events that all seem to be interconnected. Diseases, environmental mishaps, and numerous other incidents all comprise “The Pattern,” and they set the stage for the rest of the series.
The show eventually develops beyond "The Pattern," but the revelation of who is behind it, why, and what that reveals about reality, is excellent and remains the show's most immersive mystery, and undoubtedly its most important.