Tricia Helfer as EDI
You know her as: Number 6 (Battlestar Galactica), Veronica Dare (Halo 3: ODST)
Tricia Helfer gained her nerd cred as Six in BSG, but little did we know that the sexiest cylon in the galaxy would also turn out to be the sexiest anthropomorphic cyborg A.I. in the Mass Effect series. Although she's been around since number two, she didn't gain that bangin' metal body until the trilogy's finale. We're pretty sure Joker was in love with her even before that, though.