3. Slippy ToadGAME: StarFox 64 (N64, 1997)
Half-frog, half-humanoid, 100% annoying. Ten times out of ten you'd rather just shoot him out of the sky instead of your enemy because of his annoying request to save him. And jeez, for a member of the prestigious Star Fox crew, you'd THINK he wouldn't get into so much trouble and need you to bail him out so often. Falco may be an asshole, and Peppy might be insane, but at least they don't make you want to strangle them.