The next time you find yourself posting a comment (like you may well do after reading this list) or replying with a snarky quote to some sobbing attention-seeker on Facebook, take a moment to consider its origin, especially if you pull out a “c-c-c-combo breaker” or congratulate someone with the words “a winner is you!” – you're tapping into some of the greatest video game-related memes of all time. And while we know there are far more than fifty, we've put together a list that should keep you going for quite a while. If you've not been keeping up with the times, you might even find yourself learning a thing or two. Sit back and enjoy the ride as we count down 50 of the greatest video game memes ever.