The French Revolution
We've seen Les Miserables (the movie and the stage show). Isn't it time to play the video game? The French people's fight for Enlightenment—equality, inalienable rights, not getting beheaded for splashing mud on the king's poodle—at the end of the 18th century would certainly resonate in today's political climate.
America seems on the brink of class warfare as it is, and exploring the French Revolution on a dramatic, human level—say, in a video game—might get gamers that much interested in a real-life political revolution. At least maybe it would inspire us to get off our asses and vote.
Plus it would be fun to play as a the small-in-stature but big-in-presence Napoleon Bonaparte, equipping platform clogs and using skill points to buy taller horses so the troops will actually take us seriously.