It looks like Peter Griffith might have something to say about Charlie Sheen. Comedy Central has announced that Family Guy creator Seth MacFarlane will handle MC duties at the Charlie Sheen Roast this fall.

“I’m very excited to work with Comedy Central again on the roast,” MacFarlane said in a statement. “Charlie is a true icon with a talent that is strong and pure and concentrated into small crystals which can be smoked or eaten.”

Let the laughs begin?

The Charlie Sheen roast will air on Sept. 19, the same day that Two and a Half Men premieres on CBS. Wonder which will get higher ratings.

[via EW]