1. ANTHONY HOPKINS AS DR. HANNIBAL LECTER IN THE SILENCE OF THE LAMBS (1991)
Playing the now-iconic serial killer Hannibal Lecter, Anthony Hopkins took a character from author Thomas Harris’ same-named novel and turned it into the world’s most charismatic flesh-eater. Sure, Lecter feasts on human coverings and insides with the class of a rich man snacking on caviar, but he’s someone who’ll simultaneously drink high-priced Chardonnay. With intelligent discourse and a velvety smooth pitch, Lecter is the most dangerous kind of villain: A brilliant charmer who’s also a skin-devouring baddie. Your mother would be defenseless.