21. Big Ben to Holmes FTW
Super Bowl: XLIII
Matchup: Steelers vs. Cardinals
Location: Tampa, FL
Prior to Super Bowl XLIII, the Pittsburgh Steelers were tied with the Cowboys and 49ers for most Super Bowl titles for a franchise with five. After Larry Fitzgerald hauled in a 64-yard touchdown pass to put the Cardinals up by three with 2:37 to play, it looked like the Steelers would remain in that ignominious three-way deadlock. However, quarterback Ben Roethlisberger drove his team 78 yards down the field, delivering their sixth championship with an incredibly precise six-yard touchdown pass to game MVP Santonio Holmes. The catch, which Holmes made between three Cardinals while dragging the tips of his toes inbounds, has to go down as one of the best in Super Bowl history.