5. DJ Khaled f/ Akon, T.I., Rick Ross, Fat Joe, Birdman & Lil Wayne "We Takin' Over" (2006)
Album: We the Best
Label: Terror Squad, Koch
With some very phoned-in appearances from T.I., Fat Joe and Rick Ross, "We Takin' Over" could very well have been yet another generic entry in what would eventually become an endless series of completely boring Khaled-helmed posse cuts...if it wasn't for Wayne.
After a brief but effective setup by Birdman, Weezy seizes control of the track for his unforgettable cleanup verse: "I am the beast/Feed me rappers or feed me beats/I'm untamed I need a leash /I'm insane I need a shrink."
And if that wasn't enough to claim the beat as his own, he revisited it on his Da Drought 3 tape with a sprawling new verse in which he handles the recently broken Birdman-kissing scandal in the swiftest way possible-with an admission: "Damn right I kissed my Daddy/I think they pissed at how rich my Daddy is."