Artist: Michelangelo
Location: Vatican City
Year Created: 1508-1512

There's a reason that the Sistine Chapel is a must-see destination for tourists who come to the Vatican. Just consider the chapel as the house of Michelangelo, as the walls and iconic ceiling are covered in his High Renaissance handiwork (though the walls also boast paintings by Sandro Botticelli, Domenico Ghirlandaio, and Piero Perugino too). The Sistine Chapel will take a viewer's breath away, as its expansive surface is covered in nine scenes from the Book of Genesis. It even includes Michelangelo's most famous Creation of Adam.