Year: 1976
Game: Buffalo Bills vs. Detroit Lions
Fail: O.J. took a lot L's later on in life, but he really can't be blamed for this one. While the Juice carved up the Detroit defense for 273 yards (an NFL record at the time), his team still went on to lose 27-14. The Bills started second string QB Gary Marangi, who had a QB rating of 19.7 for the game.