The 50 Biggest Upsets in March Madness History

#21. If At First You Don't Succeed... (1980)

Score: #8 UCLA 77, #1 DePaul 71

These days, we're pretty sure DePaul fans (anyone? anyone? Bueller?) would take a second-round "upset" against UCLA any day of the year. Back in 1980, this was a travesty...

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