First appearance: Marvel Spotlight #32 (1977)
If Marvel really wants to confuse thousands of moviegoers all at once, it should definitely launch a Spider-Woman movie. On the surface, Jessica Drew sounds like the long-lost cousin of the Wall Crawler, but in all actuality she has very little to do with Peter Parker. She was simply created and trademarked by Marvel so that no other company could.
It's not that she's a boring character, it's just that for movie audiences, the idea of Spider-Woman would probably just come across as silly. Much like we said about the She-Hulk earlier, it's hard enough to get their male counterparts right, and if Marvel tries to introduce their female equivalents it would probably just turn people off.