City: Washington, D.C.
Also Destroyed In: Category 7: The End of the World; 2012; and Mars Attacks!
Though every last one of us on the Complex Staff are fucking patriots, it's nice to see the White House blown up once in a while. Even you red-state patriot nut jobs have to admit you'd rather see it blown up than watch a dumb Disney movie where the president's kids get into wacky hijinks. You can see the poster for the best movie set at the White House here.
Also, no discussion of Independence Day can ignore the greatest speech in cinema history.