16. Issac Clarke
Game: Dead Space
Engineering star Isaac Clarke lives through the events of Dead Space killing disgusting Necromorphs all the while on a mission to rescue his girlfriend on a messed up spaceship. He later wakes up in a mental hospital suffering from dementia all the while still having to kick major necromorphs butt. Any normal person would be confused to the point of submission, but not our Clarke. He fights on regardless of how crazy he or things around him become.