The Biggest First-Round Upsets in NBA History

10. (8) Philadelphia 76ers vs. (1) Chicago Bulls

Season: 2012
Series: 76ers in six.

Chicago was up by 12 with a minute and some change left to play in Game 1 when Derrick Rose went up for a layup and fell to the ground holding his knee. That's when the Bulls lost the series. Deflated and without their best player, Chicago then lost Joakim Noah to a sprained ankle in Game 3. Philly took advantage and eventually beat Chicago in six. Andre Iguodala hit a pair of free throws in the series-clincher with two seconds left to pull off the upset. This isn't a huge upset given the factors that were in play, but you got to give the 76ers props for smelling blood in the water.

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