45. Michigan's Misery
Game: Appalachian State Mountaineers @ Michigan Wolverines
Before the stock market crash of '08, Vegas crashed in '07 when the mighty Michigan Wolverines laid a dinosaur egg to FBS subdivision foe Appalachian State. It's supposed to work like this: upstart stays in it all game with the heavyweight, only to have said heavyweight crush their dreams with a last second field goal. Not this time. Side bar: Can you imagine the commentary if somehow dude who picked up the block fumbled the ball and UM returned it for a score? Fall on the ball, homie, fall on the ball!