The 50 Biggest Upsets in March Madness History

#42. The Cardinal Feels Blue (2000)

Score: #8 North Carolina 60, #1 Stanford 53

Let's put it this way: Mark Madsen (hard to believe this guy got into Stanford, huh?) had nothing to dance about after the Cardinal squandered their first No. 1 seed in school history in the second round of the tournament.

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