Have you ever gotten a good look at GLaDOS? Initially she looks like a vacuum cleaner flipped upside down, just a bunch of cables and gears, but if you look closer 'she' kind of looks like a human being flipped upside down.
Jeremy Bennett, the game's art director, says that was intentional,
"Eventually, we settled on a huge mechanical device with a delicate robotic figure dangling out of it, which successfully conveys both GLaDOS' raw power and her femininity."
Some people think she looks more like a woman who has been bound and gagged. Take a look at the image above and tell us GlaDOS doesn't look bizarrely similar to the woman on the right.