Album: Mezzanine (1998)
Video Game: Assassin's Creed (2007)

If you weren't looking at the TV screen, you'd think that Fox's medical drama House was coming on but alas, it the commercial for Assassin's Creed. Depending on how you ask, watching Altaïr ibn-La'Ahad stalk his prey to Massive Attack's "Teardrop" is a lot more interesting than seeing Hugh Laurie's grizzled mug and a bunch of gory doctor stuff.

Watch the Assassin's Creed commercial:
 

Listen to "Teardrop" on Spotify:

And for farts and giggles, the opening to House: