City: New York, NY
Address: 96 Lafayette St.
Capacity: 480 upstairs, 300 downstairs
Coolest Feature: Custom-made speakers (honorable mention: the smoke machine)

Located right between Walker and White Streets, Santos Party House walks the line between Chinatown and Tribeca. The multipurpose space opened in 2008, acting as a subterranean home to parties hosted by Diddy and Va$htie. DJ Premier and Q-Tip have blessed crowds with amazing DJ sets, but Santos is also responsible for hosting various performances ranging from strange to amazing.

Co-owned by Andrew W.K., Santos was sold out in February 2011 thanks to Odd Future's first New York City performance and A$AP Rocky shut it down in a similar fashion later that year. At the end of last year, Trinidad James headlined his very first show, slapping the industry in the mouth just a week before signing a multimillion dollar deal with Def Jam.