Game: The Castlevania series (1986-2013)

Immortal. Prince of Darkness. Need for blood. These characteristics alone should make Stoker's nosferatu an entry on this list. However, it is staying power that makes the Count so formidable. He's battled untold generations of vampire-hunters including the entire Belmont family. Most amazing are his multiple levels of battle during fights (he can hurl fireballs, change into a giant bat or demon.) Dracula rarely ever ends in just one form. Grab all the stakes you can.