Partner: Patrick Dempsey
Seriously, though, how could McDreamy not have a totally hot wife in real life? Of course he does! But she isn't the stay at home type. Mrs. Dempsey is a makeup artist to the stars whose work has been captured in everything from big budget movies to fashion editorials. So, not only is she a looker, but the fact that she's self-made increases her stock ten fold. Good catch, Demps.