Major Hit: "Just A Friend" (1989)

Other Hit: "Vapors" (1988)

Calling Biz Markie a one-hit wonder is not unlike calling Leonardo Da Vinci a cartoonist. Although his comedic yet tender ballad "Just A Friend" became a Top 10 single in 1989, it was all his work with the Juice Crew that made him a seminal figure in hip-hop culture. Just try to imagine a world without songs like "Pickin' Boogers" and "Make The Music With Your Mouth Biz"—to say nothing of his funky features with groups like De La Soul (who are also not one-hit wonders). So why did VH1 put Biz on their 2002 list of One-Hit Wonders? Guess they must have caught "The Vapors."