Apparently, it’s not always about the laughs with Bill Hader and Kristen Wiig. The former Saturday Night Live castmates who have worked together in so many silly, absurd sketches have ramped up the seriousness for their movie The Skeleton Twins.

The film also stars Luke Wilson and Ty Burrell, and centers around the estranged, titular twins (Hader and Wiig), their attempted suicides on the same day, and the impact it has on their lives after they both survive. The film debuted to strong reviews this past January at Sundance, winning the Screenwriting Award: U.S. Dramatic.

The trailer is above, and you can check it out when it is released on September 19.

[via Vulture]