As Seen In: "Charlie Has Cancer" (Season 1)
Location: 26th St. Benjamin Franklin Parkway

Written by Philly native Rob McElhenney (Mac), this early episode (originally shot as the pilot) follows Charlie as he reveals to Dennis that he's terminally ill. Of course, this prompts Mac and Dennis to do the right thing: find a woman to give him pity sex.

Two good things emerge from this episode: Charlie's healthy (he was lying), and Mac finds a new love interest: Carmen. Everything is going great for Mac and Carmen, but the couple does face one hurdle: Carmen's a pre-op transsexual. To his credit, Mac continues to date her even after learning this. They go on a date to run up the steps of the art museum, just like Rocky Balboa (and every tourist to visit the city after 1976). When they reach the top of the steps, they hug each other, though Mac avoids getting too close.

The steps of the Philadelphia Museum of Art have been immortalized by pop culture via Stallone's film, but the building itself is a national treasure. One of the largest art museums in the United States, it attracts over 800,000 people to its main building each year. The museum houses over 200 galleries that cover more than 2,000 years, with work from Pablo Picasso, Thomas Eakins, Paul Cézanne, Salvador Dalí, Claude Monet, Vincent Van Gogh, and more.

If you never visited the museum as a tourist or a student of the Philadelphia public school system, perhaps you made it out as a high-school wrestler. Many teams have run up the steps during training, and many team members have vomited as a result. It's a lot of steps, folks—72 to be exact.