Memorable Quote: "It's always something."

Always disgusting, but always charming, Radner's Roseanne Roseannadanna would gross out Weekend Update's Jane Curtin just to cheer her up with one of her traditional Rosanne Rosannadanna family songs. And by traditional, we mean she sang on late night about Bo Derek braiding her nose hairs. 

Radner, one of the original Not Ready for Primetime Players, helped define SNL, and we'd like to throw out a few honorable mentions of her characters: Emily "Nevermind" Litella, Baba Wawa and Candy Slice.