3. H.O.P.E. by Shepard Fairey, 2008
Shepard Fairey, in his usual method of transforming figures into icons, did just the same with Barack Obama. He turned a single photograph into a dominating graphic force during the 2008 Presidential Election. "Hope" not only became a buzzword that November, but the image was emblazoned on everything from posters to coffee mugs and T-shirts. While Fairey got into a lot of legal trouble for the piece, it still marks the most memorable piece of political artwork America has had in the last 10 years, at least.