Digital artist Brad Anderson created a series that casts The Simpsons with real actors from Hollywood. Anderson merged illustrated versions of Homer, Marge, Bart, Lisa, and Maggie with big names like George Clooney, Cate Blanchett, Ewan McGregor, Reese Witherspoon and Jennifer Aniston. With cameo appearances from Johnny Depp, Steve Bucemi, Dustin Hoffman and more, hit the thumbs for a closer look at real life characters from The Simpsons. [Thaeger]