On Wednesday morning, Tom Brady's appeal of his Deflategate suspension was denied by the 2nd Circuit Court of Appeals:

The news was first broken by the Associated Press:

This means that Brady only has one card left to play if he wants to continue fighting in order to try and avoid a four-game suspension. He will need to take his legal battle to the Supreme Court. However, since the Supreme Court isn't currently in session, there's almost no chance Brady's appeal would be heard before the start of the 2016-17 NFL season—and that's if SCOTUS even agreed to hear Brady out in the first place:

The seemingly never-ending #Deflategate saga appears to be approaching the end, and at this point, the beginning of the Jimmy Garoppolo era in New England appears to be inevitable. If everything plays out as expected and Brady is required to serve a four-game suspension, Garoppolo will likely start the Patriots' first four games against the Cardinals, Dolphins, Texans, and Bills.