Members of Hollywood are reacting to David Letterman's imminent retirement in a variety of ways. Jimmy Kimmel is going off the air as a sign of respect, Conan O'Brien plans to get naked, and George Clooney is in denial. He can't accept a world without Letterman on television, so he handcuffed himself to the Late Show host last night and threw the key into the crowd. Of course, Letterman couldn't resist taking the layup with a bondage joke. 

Watch video of the last-ditch effort above.