Don't get too excited just yet, but Fox confirmed today that it has been in talks for some sort of X-Files reboot. It brought back 24 recently with a limited run, which was pretty successful. Series creator Chris Carter hinted over the summer that he'd been talking to Fox.
Obviously, stars Gillian Anderson and David Duchovny would have to be on board. They're both currently on other shows, though: Duchovny is in the upcoming Aquarius, where he stars as a police detective investigating Charles Manson, and Anderson is on Hannibal and The Fall.