'Resident Evil' (1996-2012)
There are a lot of female characters in the Resident Evil series, but most of them are idiots. That's not a knock against them; most of the male characters in Resident Evil are idiots, too. But Jill stands out as the most likable, maybe because she was the original. Her evolution throughout the series has made the most sense, as well. Except when she went blonde, but that's hardly the worst thing about RE 5 in any case.