Neighborhood: Lower East Side
Address: 205 East Houston St.

If you want to take your lady on a tour of Nora Ephron's New York, this is where you kick it off. The pastrami on rye may not make her climax like Meg Ryan did, but at the very least, a foodgasm is imminent. Plus, getting full on sauerkraut-smothered Reubens is the perfect prep for your stomach before a night of potent libations at LES mainstays like Schiller's and Pianos. When you miraculously wake up sans hangover, you can thank Katz's.