9. JAY MOHR

When: March 2010
Comment: "Jay Mohr thinks I 'stumbled' past him last night. There's a big difference between stumbling by and just not interested."

Anyone who picks a fight with Handler is almost guaranteed to get a response. Jay Mohr learned it the hard and humiliating way after tweeting his encounter with Handler at the Colorado hotel they were both staying at for the respective comedy shows. Mohr tweeted, "Just saw Chelsea Handler in the lobby of my hotel. She was so drunk she could hardly walk. I think someone has a wee bit of a problem."