21. Elaine Stritch as Colleen Donaghy on 30 Rock
Jack Donaghy (Alec Baldwin) probably wouldn't be the man he is today without the tough love and nurturing—for lack of a better word—of his domineering mother Colleen. Still, it's not hard to imagine how rough life with her as a mother must've been, especially when Jack's childhood to-do list included "Hit Mom With a Car," which he later did. By "accident." Sure it was, man.